The Bill Priest Institute is home to the headquarters for the North Texas Small Business Development Center, which oversees the operation of 17 SBDCs throughout the 49-county North Texas area. The following SBDCs are hosted by DCCCD entities in partnerships with the SBA:

• Best Southwest SBDC, located at Cedar Valley College
• Dallas SBDC, located at the Bill Priest Institute
• Risk Management SBDC, located at the Bill Priest Institute
• International SBDC, located at the World Trade Center, hosted by the Bill Priest Institute
• Government Contracting SBDC, located at the Bill Priest Institute
• Technology Assistance SBDC, located at the Bill Priest Institute